Lo Han Guowepụ bụ icha mmirimmiri odo ntụ ntụ ka agba aja aja wepụ. Ọ na-atọ ụtọ nke ukwuu, ugboro 240 na-atọ ụtọ karịa sucrose, dị nso na shuga, na-enwe ntakịrị licorice dị ka ụtọ. Ebe mgbaze nke mogroside dị ọcha bụ 197-201 Celsius. Ọ na-adị mfe mgbaze na mmiri na ethanol.
Ọrụ:
1.Mkpụrụ Mkpụrụ MọnkA na-eji (Mogroside) na ọgwụ ọdịnala ndị China maka oyi, ụkwara, akpịrị akpịrị, ahụ erughị ala afọ, enwere ike iji mee ka ọbara dị ọcha.
2. Mkpụrụ mkpụrụ osisi Monk (Mogroside) dị mfe soluble na mmiri na enweghị ọdịda.
3. Mogroside nwere nnukwu amino acid, fructose, vitamin na mineral. A na-ejikwa ya na nri ndị China ọdịnala dịka ihe mgbakwunye ose na ihe oriri. Dị ka ihe na-atọ ụtọ eke zuru ụwa ọnụ, ọ bụ ezigbo nnọchi maka sweeteners artificial dị ka aspartame. Enwere ike iji ya na ihe ọṅụṅụ, ngwaahịa esi nri, nri na-edozi ahụ, nri ndị nwere obere kalori ma ọ bụ nri ndị ọzọ na-achọ obere ma ọ bụ enweghị ihe ụtọ carbohydrate ma ọ bụ obere ma ọ bụ enweghị calorie. Isi nri ma ọ bụ ime achịcha anaghị emetụta ụtọ ya ma ọ bụ ụtọ ya.
Mmetụta ọgwụ
(1) Mmetụta na-atụ anya: Mogroside (mkpokọta glycosides> 80%) 0.2g / kg, 0.4g / kg, 0.8g / kg ka a na-enye intragastrically. Usoro nke 0.4g / kg na 0.8g / kg mụbara ụba nke tracheal secretions na oke, na-egosi mmetụta dị ịrịba ama na-atụ anya.
(2) Mkpochapụ akpa ume na mmetụta antitussive: Mogroside (mkpokọta glycosides> 80%) 0.2g / kg, 0.4g / kg, 0.8g / kg budata belata ọnụ ọgụgụ nke ụkwara na ụmụ oke nke amonia kpatara, mana enweghị mmetụta dị ukwuu na ya. oge incubation nke ụkwara amonia kpatara.
(3) Mwepu radical na mmetụta antioxidant:
a.Mogroside wepụ(Mogroside) (ngụkọta glycosides ≥ 98%, ọdịnaya Mogroside V 65.20%) nwere mmetụta na-akpachapụ anya na radicals free hydroxyl na radicals free oxide anion. Site na mmụba nke ntinye nke Mogroside wepụ, mmetụta scavenging na-abawanye nke nta nke nta, na-egosi njikọ ụfọdụ dose-mmetụta;
b. Mwepụta Mogroside nwere mmetụta mgbochi dị ukwuu na mmeghachi omume hemolysis oxidative nke oke RBC n'oge incubation in vitro. Na nso nke 0.04-1.15 mg / ml, ọnụ ọgụgụ mgbochi nke Mogroside wepụ na erythrocyte autooxidative hemolysis bụ karịa 50%, na Mogroside wepụ nwere mmetụta nchebe dị mma na RBC autooxidative hemolysis;
c. Mmetụta nchebe nke Mogroside wepụ na RBC autooxidative hemolysis anaghị egosi mmekọrịta dose-mmetụta. Usoro kachasị mma bụ 0.46 mg / ml, yana ọnụego mgbochi nke 85.55%;
d. Malondialdehyde (MDA) bụ ngwaahịa njedebe nke peroxidation lipid na enwere ike iji nyochaa ike nke peroxidation lipid. Mogroside wepụ nwere mmetụta mgbochi siri ike na mmepụta nke MDA n'oge oke erythrocyte autooxidation hemolysis;
na.Mogroside wepụnwere mmetụta mgbochi dị mma na mmepụta nke MDA na-akpaghị aka na imeju imeju homogenate. Mmetụta mgbochi kachasị mma na ntinye nke 0.875 mg / ml, na-eru 23.63%; f. Mogroside wepụ nwere ike igbochi lipid peroxidation na oke imeju anụ ahụ, nwere mmetụta nchebe na imeju anụ ahụ peroxidation mmebi nke Fe na H2O2 kpatara, ma nwee ike ibelata ihe omume nke hemolysis erythrocyte; Mogroside nwere ike igbochi mmepụta MDA nke ọma na mitochondria imeju, na mgbochi ya na-abawanye na mmụba nke itinye uche.
(4) nkwalite mgbochi:
Nlekọta ọnụ nke mogroside na nkịtị na cyclophosphamide (CTX) - ụmụ oke na-ekpochapụ enweghị mmetụta dị ịrịba ama na ọrụ mgbochi nke ụmụ oke nkịtị, mana ọ ka mma macrophage phagocytosis na T cell proliferation nke CTX-suppressed ụmụ oke. Nke a na-egosi na mogroside nwere mmetụta nchịkwa dị mma na ọrụ mgbochi cellular nke ụmụ oke CTX kwụsịrị.
(5) Mmetụta na shuga ọbara:
Otu nchịkwa ọnụ nke 30% mogroside 200 mg/kg enweghị mmetụta dị ịrịba ama na ọdịnaya shuga ọbara na ọrụ enzyme imeju nke ndị okenye nwere ahụike.MogrosideV bụ ihe ụtọ dị mma nke na-adịghị emetụta ọdịnaya shuga dị n'ọbara nke ndị nkịtị.
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(6) Mmetụta mgbochi ọrịa kansa:
Iji DMBA dị ka onye mmalite na TPA dị ka carcinogen, a na-eme nnwale anụ ahụ nke akụkụ abụọ nke carcinogenicity; carcinogenicity na-egbu oge nke mogroside bụ otu ma ọ bụ dị ike karịa nke stevioside, na-egosi na ọ nwere mmetụta mgbochi ọrịa cancer. Ya mere, enwere ike iji mogroside mee ihe dị ka onye na-egbochi ọrịa cancer.
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Oge nzipu: Ọgọst-23-2024
