Coenzyme Q10 bụ naanị coenzyme Q dị n'ahụ mmadụ, nke a makwaara dị ka ubiquinone. E gosiputara na Coenzyme Q10 nwere antioxidant, ihe nchacha nke radical free, mgbochi tumor ma melite mmetụta mgbochi mmadụ, si otú a na-ebelata ike ọgwụgwụ na imeziwanye ikike mmega ahụ, na mgbochi ịka nká. Na mmetụta ahụike dị iche iche dịka nchebe obi.
otu,Ọrụ physiological nke coenzyme Q10
1. Free radical scavenging na antioxidant ọrụ (na-egbu oge ịka nká naịma mma)
Coenzyme Q10 dị na steeti abụọ: belata na oxidized. N'ime ha, mbelata coenzyme Q10 na-adị mfe oxidized na nwere ike igbochi peroxidation nke lipids na protein na scavenge free radicals. Belata nrụgide oxidative, nke bụ mmetụta ọjọọ nke free radicals na-emepụta na ahụ bụ ihe dị mkpa na-eduga na ịka nká na ọrịa. Coenzyme Q10 bụ antioxidant dị irè na nke na-eme ka ọ ghara imebi ihe nke nwere ike belata mmebi nke nrụgide oxidative kpatara.Coenzyme Q10 nwere ike imeziwanye bioavailability nke akpụkpọ ahụ, mee ka akpụkpọ ahụ dịkwuo mma, mee ka ntinye nke keratinocytes dịkwuo elu, melite ikike antioxidant nke mkpụrụ ndụ akpụkpọ anụ, na-egbochi ịka nká, ma nweta mmetụta ọgwụgwọ na dermatitis, otutu, bedsores, ọnya anụ ahụ na ọrịa anụ ahụ ndị ọzọ. Coenzyme Q10 nwekwara ike ịkwalite nguzobe nke mkpụrụ ndụ epithelial na benignization nke anụ ahụ granulation, gbochie ọkpụkpụ, ma kwalite nrụzi; na-egbochi ọrụ phosphotyrosinase, gbochie ịmepụta melanin na ntụpọ gbara ọchịchịrị; belata omimi nke wrinkles, melite dullness akpụkpọ; ma nwee ike ịbawanye nghọta Mgbasa nke amino acid na-abawanye ọdịnaya mmiri nke akpụkpọ ahụ; ọ na-enwe mmetụta dị mma n'ịkwalite ụda akpụkpọ ahụ na-adịghị mma, na-ebelata wrinkles, na iweghachi akpụkpọ ahụ mbụ ire ụtọ, elasticity na moisturizing Njirimara.
2. Kwalite mgbochi mmadụ na mgbochi tumor
N'ihe dị ka afọ 1970, nchọpụta ndị dị mkpa kọrọ na ịṅụ coenzyme Q10 n'ime ụmụ oke nwere ike ịbawanye ọrụ nke mkpụrụ ndụ na-alụso ọrịa ọgụ na-egbu nje bacteria, melite nzaghachi mgbochi, ma kpalie mmụba nke ọnụ ọgụgụ nke immunoglobulins na ọgwụ nje. Nikbakht et al. mụọ na mgbe ndị nwoke na-eme egwuregwu na-ewere Coenzyme Q10 mgbe asọmpi na-esochi, ọnụ ọgụgụ nke neutrophils na plasma ha belatara nke ukwuu. Ya mere, ha kwenyere na Coenzyme Q10 bara uru iji kpuchido usoro ahụ ji alụso ọrịa ọgụ na ịkwalite mgbochi ahụ. Maka ndị nkịtị, iji ọnụ na-ekwu Coenzyme Q10 mgbe ịrụbiga ọrụ ókè nwere ike ime ka ike ọgwụgwụ ahụ dịkwuo mma ma welie ahụ ike.
Nnyocha e mere n'afọ ndị na-adịbeghị anya egosila na coenzyme Q10, dị ka ihe na-eme ka ahụ ghara ịgbasa ọrịa ahụ, nwere ike ịrụ ọrụ dị mma n'ịkwalite ihe mgbochi ahụ na mgbochi tumor, ma nwee mmetụta ọgwụgwọ ụfọdụ na ọrịa cancer metastatic dị elu.
3. Mee ka ike obi dị ike ma welie ike ụbụrụ
Coenzyme Q10 bụ otu n'ime ihe kachasị mkpa na ahụ mmadụ. Ọdịnaya ya dị oke elu na myocardium. Mgbe ọ na-adịghị, ọ ga-eme ka obi ghara ịrụ ọrụ nke ọma, na-ebute mgbasa ọbara na-adịghị mma, ike ịrụ ọrụ obi na-ebelata, ma mesịa bute ọrịa obi. Isi mmetụta nke coenzyme Q10 na myocardium bụ ịkwalite phosphorylation cellular oxidative, melite myocardial ume metabolism, ibelata ischemia mebiri myocardium, na-abawanye mmepụta ọbara obi, melite mkpọchi na-adịghị ala ala na iguzogide arrhythmias, si otú ahụ na-echebe myocardium. Melite ọrụ obi ma nye ike zuru oke maka myocardium. Nnyocha ụlọ ọgwụ na-egosi na ihe karịrị 75% nke ndị ọrịa obi na-arịa ọrịa obi emewo ka ọnọdụ ha dịkwuo mma mgbe ha nwesịrị Coenzyme Q10. Coenzyme Q10 bụ onye na-arụ ọrụ metabolic nke nwere ike ime ka iku ume cellular rụọ ọrụ, na-enye oxygen na ume zuru ezu na cardiomyocytes na ụbụrụ ụbụrụ, na-eme ka sel dị mma ma dị mma, ya mere na-egbochi ọrịa obi na ụbụrụ cerebrovascular.
4. Mezie ọbara lipids
Ka ha na-ebelata lipids ọbara, statins na-egbochikwa njikọ nke onwe nke coenzyme Q10. Ya mere, ndị mmadụ nwere oke lipids ọbara ga-ewere coenzyme Q10 mgbe ha na-ewere statins iji nweta mmetụta dị ala nke lipid ka mma. Coenzyme Q10 nwere ike ibelata ọdịnaya nke lipoprotein dị ntakịrị nke na-emerụ ahụ mmadụ, gbochie lipoprotein dị ntakịrị ịbanye n'ime oghere sel endothelial, belata nguzobe nke lipids na mgbidi dị n'ime akwara, ma gbochie lipids ịmepụta atherosclerotic. plaques na intima nke arịa ọbara. , ka ị na-abawanye ọrụ nke lipoprotein dị elu, na-ewepụ ngwa ngwa ihe mkpofu, toxins na plaques kpụrụ na mgbidi dị n'ime arịa ọbara, na-achịkwa lipids ọbara na igbochi nhazi nke atherosclerosis.
abuoNchekwa nke Coenzyme Q10
Ahụ mmadụ enweghị ọkwa dị elu nke Coenzyme Q10 mgbe a mụrụ ya, mana ọdịnaya na-erute elu ya n'ihe dị ka afọ 20. Mgbe afọ 25 gasịrị, ikike ịmepụta Coenzyme Q10 ji nwayọọ nwayọọ na-ebelata. Ka afọ na-abawanye, Coenzyme Q10 dị n'akụkụ ahụ na anụ ahụ dị iche iche na-ebelata nke nta nke nta, na Coenzyme Q10 dị n'ime obi na-ebelata nke ukwuu. Mgbe ọdịnaya nke Coenzyme Q10 na ahụ mmadụ na-ebelata site na 25% N'ọdịnihu, ọrịa dị iche iche ga-eme, ya mere mgbakwunye exogenous nke Coenzyme Q10 dị ezigbo mkpa. Akụkụ dị ịrịba ama nke Coenzyme Q10 bụ na ọ naghị egbu egbu, na-abụghị teratogenic na enweghị mmetụta doro anya, ọ dịkwa mma maka iji ụlọ ọgwụ eme ihe. Coenzyme Q10, dị ka otu n'ime coenzymes kachasị mkpa na ahụ mmadụ, ka a na-ejikarị na nlekọta ahụike.
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Oge nzipu: Feb-26-2024
