Na mgbakwunye na mgbanwe ndụ na ịrapagidesi ike n'àgwà ọma, mgbakwunye nke ihe ndị sitere n'okike na-egbochi ịka nká bụkwa ụzọ dị mfe ma dị mfe igbochi ịka nká. Dabere na ntụzịaka nyocha (NAD + usoro metabolic) yana nsonaazụ nyocha nke ịka nká ugbu a yana ngwa ndị na-echegbu onwe ya.nakwa nke"ụbụrụ ụbụrụ"mgbe COVID-19 gasịrị,anyi'ọ ga-amasị m iwebata ọtụtụ ihe ọmaihe mgbochi ịka nkásite na mgbakwunye ire ahịa na-ekpo ọkụ na Amazon.
1. NAD + ihe mgbakwunye (NMN, NR, NADH)
Ọkwa NAD + na-agbada na afọ, na-eduga na mmebi nke nwere mmetụta na ọkwa NAD +. Ezinụlọ acetylase (sirtuins, nke a na-akpọsakarị dị ka ndị na-edozi ogologo ndụ) enweghị ike ịnọgide na-arụ ọrụ nkịtị, nke mere na ọtụtụ ọrụ ndị bara uru maka ahụike nke sirtuins na-arụ ọrụ na-enweghị ike ịrụ ọrụ, nke bụ otu n'ime ihe ndị dị mkpa kpatara ịka nká.INMN (nicotinamide mononucleotide), NR (nicotinamide riboside) ma ọ bụ NADH (nicotinamide adenine dinucleotide) nwere ike inyere mkpụrụ ndụ aka ịbawanye ọkwa NAD +, ndị a na-adịkarị na sel na nri eke..Ugbu a, enwere ọtụtụ narị ọmụmụ ụlọ ọgwụ na NMN, NR, na NADH, na-elekwasị anya n'akụkụ dị iche iche dịka mgbochi ịka nká, ọrịa shuga, metabolism, na cognition.
2. Pyrroloquinoline quinone (PQQ)
PQQ bụ coenzyme redox na antioxidant siri ike. Ọ dịkwa na nri dị iche iche. Ọdịnaya nke PQQ na ahụ mmadụ dị obere. PQQ dị na sel mmadụ nwere ike isi na nri ma ọ bụ microorganisms pụta. Nri nwere ọtụtụ PQQ gụnyere: natto, pasili, tii green, mkpụrụ kiwi, pọpọ, tofu, wdg. Uru ahụike PQQ nwere ike ime gụnyere: imezi ụra, mgbochi ọrịa shuga, mgbochi ọrịa ogbu na nkwonkwo, mgbochi osteoporosis, ibelata mmerụ ahụ ischemia-reperfusion nke obi, igbochi tyrosinase, meziwanye ọmụmụ.
3. Fisetin
Fisetin, nke a makwaara dị kaNa-ewepụ osisi anwụrụ ọkụ , bụ flavonol sitere na osisi na ụcha osisi a na-ahụkarị nke a na-achọta n'ọtụtụ akwụkwọ nri na mkpụrụ osisi dịka strawberries, apụl, persimmons, eyịm, na kukumba. Ọ na-abawanye ndụ ụmụ oke ndị merela agadi site na 10%, na-ebelata akara ịka nká na anụ ahụ, ma na-ebelata ọrịa ndị metụtara ịka nká. Usoro mgbochi ịka nká nke fisetin bụ na ọ nwere ike wepụ mkpụrụ ndụ senescent ma mee ihe dị ka synolytic. Mkpokọta nke mkpụrụ ndụ senescent bụkwa ihe dị mkpa na-akpata ịka nká na ọrịa ndị metụtara ịka nká. Nnyocha achọpụtala na uru ahụike nke fisetin nwere ike ịgụnye: mgbochi oxidation, mgbochi mbufụt, nchebe obi, nchebe nke uche, igbochi oke ibu na nsogbu metabolic.
4. Urolithin A
Urolithin A dị n'ime anụ ahụ dị iche iche nke ahụ mmadụ. Ma urolithin A abụghị ihe e kere eke dị na nri ma na-emepụta ya site na ụfọdụ nje bacteria na-emepụta ellagic acid na ellagitannins. Ihe mmalite nke urolithin A - ellagic acid na ellagitannins - na-achọta n'ọtụtụ nri dị iche iche, dị ka pọmigranet, strawberries, raspberries, na walnuts. Ma ahụ mmadụ nwere ike imepụta urolithin A zuru oke mgbe ọ nwesịrị ihe ndị a na-ebute ụzọ na-ejedebekwa site na ụdị microorganisms dị iche iche nke eriri afọ. Ịka nká na-eduga n'ịbelata ikike nke autophagic nke mkpụrụ ndụ, nke na-eduga ná nchịkọta nke mitochondria mebiri emebi, na-ebute nrụgide oxidative, ma na-akwalite mbufụt. Urolitin A na-eme ka ahụike mitochondrial dịkwuo mma site n'ịbawanye autophagy.
5. Spermidine
Spermidine bụ polyamine sitere n'okike nke itinye uche ya na-ebelata n'oge ịka nká n'ime mmadụ, yana enwere ike inwe njikọ n'etiti mbelata mkpokọta spermidine na mmebi nke afọ. .Mmetụta nke spermidine nwere ike ịgụnye: ibelata ọbara mgbali elu, ịkwalite nchebe antioxidant, ịba ụba arginine bioavailability, ibelata mbufụt, ibelata vaskụla akwara, na-achịkwa uto cell.
Oge nzipu: Mar-02-2023
