Na-ekwu makaberberine , Onye ọ bụla nwere ike ịbụ ntakịrị ihe na-amaghị, ma onye ọ bụla aghaghị ịma okwu a maara nke ọma: Onye ogbi na-eri coptis - ọ pụghị ịkọ ihe mgbu! Nke ahụ ziri ezi, isi ihe dị ilu na coptis bụ berberine, nke bụ berberine hydrochloride.
Berberine (BBR) bụ alkaloid isoquinoline - C20H19NO5 ewepụtara na Coptis chinensis. Ọ dị na osisi nke 10 genera na ezinụlọ 4 gụnyere Berberidaceae. Enwere ike ịmalite kristal yiri agịga na-acha odo odo site na diethyl ether, ebe mgbaze nke 145°C. Ha na-agbaze n'ime mmiri ma ghara ịsacha ya na benzene, diethyl ether na chloroform.
Nnyocha ọgwụ ọgbara ọhụrụ ekwenyela na berberine nwere nnukwu mgbochi obi mgbawa, mgbochi arrhythmia, mbelata cholesterol, mmụba nke akwara dị nro, na-eme ka nguzogide insulin dịkwuo elu, mgbochi platelet, mgbochi mkpali na mmetụta ndị ọzọ. Ya mere, ọ nwere ike ịba uru na ọrịa obi na akwara ozi. Atụmanya ngwa ya sara mbara ma dị mkpa adọtawo nlebara anya na-abawanye ụba. Dị ka nchọpụta ụlọ ọgwụ ọhụrụ si kwuo, berberine nwere mmetụta dị mma na igbochi na ịgwọ ọbara mgbali elu, hyperlipidemia, ọrịa shuga, arrhythmia, etuto ahụ na ọrịa ndị ọzọ. Berberine hydrochloride ka akọpụtala na ibelata lipids ọbara. BBR nwere ike ịhazi okwu nke nnabata lipoprotein dị ala nke LDLR ma kwalite nnabata protein LDL site na mkpụrụ ndụ imeju. BBR na-agbanwe ka ọ bụrụ dihydroberberine (dhBBR) site na nitroreductase nke eriri afọ flora gut microbiota, na-eme ka eriri afọ banye ya ngwa ngwa. Mgbe ọ gbasasịrị, a na-agbanye ya n'ime BBR n'ime anụ ahụ eriri afọ wee banye n'ọbara. Nweta mmetụta hypoglycemic na mbelata lipid. BBR nwekwara ike melite ike metabolism. Nlekọta ọnụ nke BBR na-akpali glut microbiota iji mepụta butyrate, nke na-abanye n'ọbara ma na-eme ihe na SCFAs (obere yinye fatty acids), na-ebelata lipids ọbara na ọkwa shuga dị n'ọbara.
BBR nwere ike ịkwalite mmeghari nke mkpụrụ ndụ islet pancreatic ma nwee uru karịa ọgwụ ndị ọzọ na-egbochi ọrịa shuga. Nnwale ụlọ ọgwụ dị mkpa egosila na berberine nwere ike igbochi fibrosis myocardial na oke ọrịa shuga; BBR nwere mmetụta mgbochi platelet, nwere ike ịbawanye ọdịnaya nucleotide na platelet ma gbochie nchịkọta. Berberine jikọtara ya na statins na-arụ ọrụ dị mkpa n'ịkwụsị plasma trimethylamine oxidation na ọrịa obi na igbochi nguzobe nke atherosclerosis.
Berberine nke China bụ ezigbo nhọrọ maka ọgwụ "statin". Ebe ọ bụ na berberine dị ọtụtụ ugboro dị ọnụ ala karịa ọgwụ "statin", nchọpụta nke mmetụta mbelata ọbara-lipid berberine nwere uru na-enweghị atụ maka mgbochi na ọgwụgwọ hyperlipidemia, ọrịa shuga na ọrịa obi.
【kpọtụrụ anyị】
Ekwentị mkpanaaka: 86 18691558819
Irene@xahealthway.com
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https://healthway.en.alibaba.com/
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Oge nzipu: Jan-08-2024
